The general knowledge and understanding that every teacher of religion and science should have relative to chemistry can be found in the answers to three major questions. In my own response to the first question, How did chemistry emerge as a discipline? I trace the origins, establishment, and subsequent historical significance of cosmology. I contend that chemistry is “the obvious, oldest science” and, as such, has played a key role among the sciences in agelong human efforts to understand reality. In (...) my response to the second question, How do chemists currently view (cosmic) reality? I outline three prominent examples in support of my contention that chemistry, despite being “the obvious, oldest science,” is seen by some as playing only a tacit role in current efforts to (re)integrate religion and science. In my response to the third question, How do chemists currently view ultimate reality and meaning? I argue that “unifiers” in chemistry can also now play a key role in a reality revolution that is pointing humankind not only toward a possible historical (re) integration of religion and science but also toward a return to cosmology. (shrink)